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Электронная почта
marketing@alpharmaca.com
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Телефон
18964508029
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Адрес
Caohejing Pujiang High tech Park, Minhang District, Shanghai, China
Shanghai Alpha Meijia Biotechnology Co., Ltd
marketing@alpharmaca.com
18964508029
Caohejing Pujiang High tech Park, Minhang District, Shanghai, China
Accusizer 780APS Fully Automatic Counting Particle Size DetectoryesUsing photoresist methodSingle particle optical sensing technology(SPOS)Conduct particle size testing and counting on particle samples, detecting one particle at a time to construct a true particle size distribution. ApplicationSPOSThe statistical distribution data of particle size obtained by technology, laser diffraction, and sedimentation methods form a sharp contrast,SPOSTechnology can collect particle count information while measuring particle size.
Compared with the classical resistance method,AccuSizer780The particle size distribution obtained by the series of instruments has higher resolution and performance.AccuSizer 780The series of instruments will not miss any "tail" large particles, and thisOften determines the qualification of the tested sample.
The wide measurement range, high-speed counting rate, compatibility with liquid and gas phases, and effective prevention of blockage in test samples are the classic works of *——AccuSizer780Series of instruments.
At the same timeAccuSizer 780The series of instruments have an automatic dilution device that can automatically and quickly dilute the sample to a concentration of * and perform efficient detection and analysis. Users can eliminate errors caused by manual trial and error experiments and manual operations by simply clicking the mouse, thus saving time and labor costs to the maximum extent.
Accusizer 780APS Fully Automatic Counting Particle Size DetectorWorking principle: photoresist method (single particle optical sensing technology)SPOS)
SPOSTechnology combines the physical effects of light reduction and light scattering organically, and obtains through light reductionObtaining a larger dynamic particle size range and increasing sensitivity to small particles through light scattering has become a technology.

AccuSizer 780 ?Technical advantages:
· One step operation, fast detection (integrating automation functions such as automatic sampling, automatic dilution, automatic detection, data processing, and automatic cleaning);
· Automatic dilution, capable of detecting high concentration samples;
· Compliant with the United States PharmacopeiaUSP729, USP787,USP788, USP789, USP1788And the Chinese PharmacopoeiaCPEuropean Pharmacopoeia and Japanese Pharmacopoeia testing requirements;comply withFDARequirement: Passed EU certification;
· 512A data channel,32A custom data channel;
· Fast, high-resolution, and highly sensitive detection of particle distribution at the tail end of the sample;

AccuSizer 780Application fields:
· Pharmaceutical field: emulsions, injections, liposomes, colloids, suspensions, polymers, viruses, vaccines, etc;
· semiconductor: CMP SlurryChip and wafer processing, etc;
· Special Chemicals: Ink&Inkjet, nanomaterials, chemical dyes, lubricants, cleaning agents, etc.
Other: filtration products, cleanliness, food and beverage, cosmetics, etc
Stability of proteins:
Factors affecting stability:
There are two forms of protein instability: chemical instability and physical instability.
① Chemical instability is caused by modifications and changes in amino acid residues. There are mainly several reactions: oxidation, reduction, deamidation, hydrolysis 、 B - Elimination and racemization?.
② Physical instability involves changes in the secondary, tertiary, and quaternary structures of proteins. These changes can be caused by various factors such as temperature PH、 And denaturing reagents, etc
Unstable phenomenon:
① Stratification: refers to the phenomenon in which proteins gradually aggregate in the upper or lower layers during the placement process.
② Flocculation: Refers to the aggregation of proteins into clusters but still maintaining the complete dispersion of each protein without showing a merging phenomenon.
③ Sourness: refers to the phenomenon of protein denaturation caused by external factors (light, heat, air, etc.) and microbial action.
The application of proteins
Mainly used as transportation carriers, antibodies, enzymes, hormones, etc. in the pharmaceutical industry.
Quality standards for proteins
According to different application pathways of proteins, their quality requirements also vary, making it difficult to establish a unified quality standard. But the stability of proteins can be determined by the distribution of protein particle size.
PSS can provide a standardized solution for protein particle size detection
The determination of the distribution of large particle tails is carried out using the principle of extinction method and large particle counting technology to determine the Large in Figure 1-
Diameter Tail section.